BDBM50352055 CHEMBL549618
SMILES OC1(CNC(=O)c2cc(ccc2Cl)-c2cc[nH]n2)CCCCCC1
InChI Key InChIKey=RYMGBXRKZKAPEA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50352055
Affinity DataIC50: 180nMAssay Description:Antagonist activity at P2X7R expressed in LPS-activated human monocytes assessed as inhibition of ATP-induced IL-1beta release in presence of low ser...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as effect on BzATP-induced Yo-Pro uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Antagonist activity at P2X7R expressed in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL-1beta releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced YO-PRO-1 uptakeMore data for this Ligand-Target Pair